Question:

What is the advantage in clinical use of humulin (human insulin: produced through rDNA technique) over use of conventional ox or pig insulin?

Updated On: Jun 21, 2022
  • It does not cause immunological problems
  • It is cheaper for the ?patient.
  • It is produced by E.coli in our own intestine.
  • There is no advantage
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The Correct Option is A

Solution and Explanation

Earlier, insulin for curing diabetes was used to be extracted from pancreas of slaughtered pigs and cattle. This conventional insulin was slightly different from human insulin and its over use resulted in some undesirable side effects, e.g. certain immunological problems such as allergy. However, humulin produced through rDNA technique is similar to that of human insulin and does not cause any immunological problems. It is thus advantageous over conventional type of insulin.
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Concepts Used:

Applications of Biotechnology

Biotechnology is the technology that utilizes biological systems, living organisms, or parts of this to develop or create different products.

For example, brewing and baking bread fall within the concept of biotechnology (use of yeast (= living organism) to produce the desired product).

Agriculture

Alternative to conventional farming: A possible solution is the use of genetically modified crops which is an alternative path to conventional farming.

Medicine 

In the area of healthcare, recombinant DNA technological processes have made an immense impact which enables the mass production of safe and more effective therapeutic drugs.

Gene Therapy 

A collection of methods that allows the correction of a gene defect that has been diagnosed in a child/embryo is called Gene Therapy.

CRISPR technology

For editing genomes, CRISPR is a simple yet powerful tool which allows researchers to easily alter DNA sequences and modify gene function.