Question

What is OHSS?

Hint:

OHSS is most common after ovarian stimulation for in vitro fertilization (IVF) and requires careful monitoring to avoid severe complications.

Answer 1

Step 1: Introduction to OHSS.
OHSS (Ovarian Hyperstimulation Syndrome) is a condition that occurs when the ovaries become excessively stimulated in response to fertility medications, particularly gonadotropins used for ovulation induction.
Step 2: Pathophysiology of OHSS.
OHSS is characterized by the following:
- Ovarian enlargement: Multiple ovarian follicles develop, leading to swollen ovaries.
- Fluid shift: Fluid leaks from the blood vessels into the abdomen, causing abdominal distention, and can lead to ascites and pleural effusion.
- Electrolyte imbalances: Electrolyte abnormalities, including hypovolemia and hypercoagulability, may occur in severe cases.
Step 3: Risk Factors.
- High doses of gonadotropins.
- Polycystic ovary syndrome (PCOS) women are at higher risk.
- Young age and low body weight.