Question

Tuberculosis (TB) is caused by Mycobacterium tuberculosis. The TB vaccine is made using

• A. Mycobacterium tuberculosis
• B. Mycobacterium bovis
• C. Tuberculin
• D. Mycobacterial DNA

Hint:

Remember, the BCG vaccine for TB is derived from an attenuated form of {Mycobacterium bovis}, not the disease-causing {M. tuberculosis}.

Answer 1

The Correct Option is B

Step 1: Understand what causes TB.
Tuberculosis is caused by the bacterium {Mycobacterium tuberculosis}, which primarily affects the lungs but can also affect other parts of the body.

Step 2: Understand the composition of the TB vaccine.
The BCG (Bacille Calmette-Guérin) vaccine is the primary vaccine used to prevent tuberculosis. It is made using a live, attenuated strain of {Mycobacterium bovis}, which is closely related to {M. tuberculosis} but less virulent in humans.

Step 3: Evaluate the options.
Option (1): {M. tuberculosis} is the pathogen, not used directly in the vaccine.
Option (2): Correct — BCG vaccine is made using {M. bovis}.
Option (3): Tuberculin is used for TB testing (Mantoux test), not vaccination.
Option (4): Mycobacterial DNA is not used in the BCG vaccine.