Question:
The substrate used during DNA replication by the enzyme DNA-dependent DNA polymerase is:
The substrate used during DNA replication by the enzyme DNA-dependent DNA polymerase is:
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DNA polymerases always use deoxyribonucleotide triphosphates (not ribose-containing ones) for DNA replication.
Updated On: Jun 17, 2025
- Deoxyribonucleotide triphosphate
- Deoxyribonucleoside triphosphate
- Ribonucleotide triphosphate
- Ribonucleoside triphosphate
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The Correct Option is A
Solution and Explanation
DNA-dependent DNA polymerase catalyzes the synthesis of DNA from a DNA template. The enzyme requires deoxyribonucleotide triphosphates (dATP, dGTP, dCTP, dTTP) as substrates. These molecules provide both the building blocks for the new DNA strand and the energy for the polymerization reaction through the hydrolysis of their high-energy phosphate bonds.
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