Question

The preference for the 20 standard amino acid residue types at each position in a given multiple sequence alignment refers to the:

• A. Pattern
• B. Profile
• C. Motif
• D. Feature

Hint:

In sequence alignments, a profile represents the preferred amino acid types at each position.

Answer 1

The Correct Option is B

Step 1: Understanding Sequence Alignment Terms 
A profile represents the distribution of amino acids or nucleotides at each position in an alignment of multiple sequences, showing which amino acids are preferred at each position. 
Step 2: Evaluating the Options 
- Pattern: Refers to specific motifs or arrangements within the sequence but not the entire sequence's residue distribution. 
- Profile: Correct, a profile captures the preference for amino acid types at each position in a sequence alignment. 
- Motif: A conserved sequence pattern often found in biological contexts but not specifically for residue preference in alignments. 
- Feature: Refers to specific sequence features or attributes but not the general residue preference in alignments. 
Step 3: Conclusion 
The term used for residue preference at each position in multiple sequence alignment is a profile.