Question

The most common cause of death in SLE in children

• A. Lupus nephritis
• B. Lupus cerebritis
• C. Libman sacks endocarditis
• D. Anemia and infections

Answer 1

The Correct Option is A

Systemic Lupus Erythematosus (SLE) is a complex autoimmune disorder that can affect multiple organ systems in the body. When considering the pediatric population, the most common cause of mortality associated with SLE must be understood in order to provide adequate clinical management and intervention strategies. Among the options provided:

• Lupus nephritis
• Lupus cerebritis
• Libman-Sacks endocarditis
• Anemia and infections

The correct answer is Lupus nephritis.

Lupus nephritis occurs when SLE causes inflammation in the kidneys, leading to significant kidney damage and potential failure. This can result in life-threatening complications if not properly treated and managed. The role of lupus nephritis as the most common cause of death in children with SLE underscores the importance of regular monitoring of renal function and early intervention.

In summary, effective management of SLE in children necessitates a focus on early detection and treatment of lupus nephritis to reduce mortality risk. Regular monitoring, appropriate medication, and timely treatments are crucial components of patient care in pediatric SLE with renal involvement.