Question

The diuretic with similarity in the structure to an antihypertensive diazoxide is _______

• A. \( \text{Furosemide} \)
• B. \( \text{Spironolactone} \)
• C. \( \text{Chlorothiazide} \)
• D. \( \text{Acetazolamide} \)

Hint:

Recognize the "thiazide" in chlorothiazide and the "diazo-" part of diazoxide might hint at a structural similarity within the benzothiadiazine class.

Answer 1

The Correct Option is C

Diazoxide is a benzothiadiazine derivative, structurally related to the thiazide diuretics. Among the given options, chlorothiazide is also a thiazide diuretic and shares a similar benzothiadiazine ring system with diazoxide. Furosemide is a loop diuretic, spironolactone is an aldosterone antagonist, and acetazolamide is a carbonic anhydrase inhibitor; these belong to different structural classes.