Step 1: Finding the Center of the Square
The given lines:
\[
x + 2y - 3 = 0, \quad 2x - y - 1 = 0
\]
represent diagonals of the square. The center of the square is their intersection.
Solving for \( x \) and \( y \):
Multiplying the first equation by 2:
\[
2x + 4y - 6 = 0.
\]
Subtracting the second equation:
\[
(2x + 4y - 6) - (2x - y - 1) = 0.
\]
\[
5y - 5 = 0.
\]
\[
y = 1.
\]
Substituting \( y = 1 \) into \( x + 2y - 3 = 0 \):
\[
x + 2(1) - 3 = 0.
\]
\[
x = 1.
\]
Thus, the center of the square is \( (1,1) \).
Step 2: Determining the Length of the Side
The area of the square is given as 16, so the side length is:
\[
s = \sqrt{16} = 4.
\]
Step 3: Finding the Required Pair of Perpendicular Sides
Lines perpendicular to the diagonals have slopes:
- Given diagonal slopes: \( -\frac{1}{2} \) and \( 2 \).
- Perpendicular slopes: \( 2 \) and \( -\frac{1}{2} \).
Using point-slope form \( y - y_1 = m(x - x_1) \) at \( (1,1) \):
1. For slope \( 2 \):
\[
y - 1 = 2(x - 1).
\]
\[
y = 2x - 2 + 1.
\]
\[
2x - y - 1 = 0.
\]
2. For slope \( -\frac{1}{2} \):
\[
y - 1 = -\frac{1}{2} (x - 1).
\]
\[
y = -\frac{1}{2}x + \frac{1}{2} + 1.
\]
\[
y = -\frac{1}{2}x + \frac{3}{2}.
\]
Multiplying by 2:
\[
x + 2y - 3 = 0.
\]
Step 4: Finding Shifted Equations
To get equations of the square sides, shift by \( \pm 2\sqrt{5} \):
\[
(2x - y - 1 - 2\sqrt{5})(x + 2y - 3 + 2\sqrt{5}) = 0.
\]
Step 5: Conclusion
Thus, the final answer is:
\[
\boxed{(2x - y - 1 - 2\sqrt{5})(x + 2y - 3 + 2\sqrt{5}) = 0}.
\]
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