The formula for the arithmetic mean is:
\[
\text{Arithmetic Mean} = \frac{\text{Sum of all observations}}{\text{Number of observations}}
\]
Given that the arithmetic mean is 45.6 kg and the number of persons is 12, we can calculate the sum of their weights by multiplying the arithmetic mean by the number of persons:
\[
\text{Sum of weights} = 45.6 \times 12 = 475.2 \, \text{kg}
\]
Thus, the sum of their weights is 475.2 kg.