Question

Some of the syndromes associated with abnormalities of sex chromosomes are:
A. Cerebral palsy
B. Klinefelter's syndrome
C. Turner's syndrome
D. Super females
Choose the correct answer from the options given below:

• A. A, B and D only
• B. B and C only
• C. A, B and C
• D. B, C and D only

Hint:

Remember the common sex chromosome aneuploidies:

\textbf{Turner Syndrome:} XO (female)
\textbf{Klinefelter Syndrome:} XXY (male)
\textbf{Triple X (Super female):} XXX (female)
\textbf{Jacobs Syndrome (Super male):} XYY (male)

Answer 1

The Correct Option is D

Step 1: Define what an abnormality of sex chromosomes is. Step 1: This refers to genetic conditions where there is an atypical number of X or Y chromosomes. The typical patterns are 46,XX (female) and 46,XY (male).
Step 2: Analyze each condition.
Step 2:

(A) Cerebral palsy: This is a group of neurological disorders affecting movement and posture. It is typically caused by brain damage before, during, or shortly after birth, not by a sex chromosome abnormality.
(B) Klinefelter's syndrome: This is a genetic condition in males caused by an extra X chromosome, resulting in a 47,XXY karyotype. This is a sex chromosome abnormality.
(C) Turner's syndrome: This is a genetic condition in females caused by a missing or partially missing X chromosome, resulting in a 45,X0 karyotype. This is a sex chromosome abnormality.
(D) Super females (Triple X syndrome): This is a genetic condition in females caused by an extra X chromosome, resulting in a 47,XXX karyotype. This is a sex chromosome abnormality.
Step 3: Identify the correct syndromes.
Step 3: Klinefelter's syndrome (B), Turner's syndrome (C), and Super females (D) are all caused by abnormalities of the sex chromosomes. Cerebral palsy (A) is not. Therefore, B, C, and D is the correct combination.