Question

Sacubitril is,

• A. ACE inhibitor
• B. Neutral endopeptidase inhibitor
• C. Calcium channel inhibitor
• D. Beta adrenergic blocker

Answer 1

The Correct Option is B

Sacubitril is a pharmacological agent that functions specifically as a Neutral endopeptidase inhibitor. Neutral endopeptidase, also known as neprilysin, is an enzyme responsible for breaking down various peptides, including natriuretic peptides which play a critical role in cardiovascular homeostasis by facilitating vasodilation and promoting natriuresis. 

By inhibiting this enzyme, sacubitril increases the levels of these beneficial peptides, thereby enhancing their effects. This mechanism makes sacubitril an important component in the management of certain heart-related conditions, often in combination with other agents to optimize cardiovascular outcomes.

The following are the provided options and the correct answer:

ACE inhibitor

Neutral endopeptidase inhibitor

Calcium channel inhibitor

Beta adrenergic blocker

The correct choice is: Neutral endopeptidase inhibitor.