Question:

Reciprocal translocation of chromosomal pieces between 9 & 22 chromosomes leads to

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Philadelphia chromosome = 9–22 translocation → CML.
Updated On: May 12, 2025
  • Cri-du-chat syndrome
  • Cystic fibrosis
  • Sickle cell anaemia
  • Chronic Myelogenous leukemia
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The Correct Option is D

Solution and Explanation

The Philadelphia chromosome, formed by translocation between chromosomes 9 and 22, causes chronic myelogenous leukemia (CML), a cancer of white blood cells.
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