One gene-one enzyme hypothesis was postulated by:
- R.Franklin
- Hershey and Chase
- A.Garrod
- Beadle and Tatum
The Correct Option is D
Solution and Explanation
Beadle and Tatum conducted seminal experiments using Neurospora crassa to demonstrate that in a multi-step biochemical pathway, distinct enzymes control each step, and each of these enzymes is determined by a specific gene. This concept is referred to as the “one gene, one enzyme hypothesis”.
So, the correct option is (D): Beadle and Tatum
Top Questions on Molecular Basis of Inheritance
- If Meselson and Stahl's experiment is continued for 80 minutes (till III generation), what would be the ratio of DNA containing N$^{15}$/N$^{15}$ : N$^{15}$/N$^{14}$ : N$^{14}$/N$^{14}$ in the medium?
- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
Construct and label a transcription unit from which the RNA segment given below has been transcribed. Write the complete name of the enzyme that transcribed this RNA.
- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
- The RNA triplet UAG acts as a stop codon which terminates the synthesis of a polypeptide. Below is given a strand of DNA which codes for four amino acids.
In which position will an insertion of a thymine nucleotide result in the termination of translation?
DNA strand:
3′ T C C A C C C G A T G C 5′- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
- The base sequence in one of the strands of DNA is: ‘TAGCATGAT’
- Give the base sequence of its complementary strand.
- How are these base pairs held together in DNA molecule?
- Explain the base complementarity rule. Name the scientist who framed this rule.
- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
Student to attempt either option-(A) or (B):
(A) Write the features a molecule should have to act as a genetic material. In the light of the above features, evaluate and justify the suitability of the molecule that is preferred as an ideal genetic material.
OR
(B) Differentiate between the following:- [(i)] Polygenic Inheritance and Pleiotropy
- [(ii)] Dominance, Codominance and Incomplete dominance
- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
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- NEET (UG) - 2025
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The output (Y) of the given logic implementation is similar to the output of an/a …………. gate.
- NEET (UG) - 2025
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- NEET (UG) - 2025
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In the above represented plasmid an alien piece of DNA is inserted at the EcoRI site. Which of the following strategies will be chosen to select the recombinant colonies?
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- Genetic Engineering and Biotechnology
Concepts Used:
Biotechnology
Biotechnology is a vast field of biology that involves the creation, production, and modification of useful products for human welfare using both the technology and the execution of living organisms and their components. An agricultural engineer, Karoly Ereky, coined the word "biotechnology" in 1919, achieving him the title of "Father of Biotechnology."
Principles of Biotechnology:
Among many, the two core techniques that entitled the birth of modern biotechnology are :
- Genetic Engineering is one of the methods of direct modifications of an organism's genome (i.e., DNA and RNA). It requires the introduction of new genes into host species to escalate function or trait, hence altering the host organism's phenotype.
- Bioprocess Engineering is one of the methods of maintaining sterile conditions to facilitate the growth of large quantities of desired microbes and other eukaryotic cells for the development of new or modified biotechnological products such as enzymes, vaccines, antibiotics, and other biotechnological products.