Question

Name the drug that disrupts microtubules and inhibits cell division.

• A. \( \text{Paclitaxel} \)
• B. \( \text{Methotrexate} \)
• C. \( \text{Cisplatin} \)
• D. \( \text{Cyclophosphamide} \)

Hint:

Think of "taxel" drugs (like paclitaxel) as microtubule inhibitors used in chemotherapy.

Answer 1

The Correct Option is A

Paclitaxel is an anti-cancer drug that belongs to the taxane class. Its mechanism of action involves binding to microtubules and stabilizing them, thereby inhibiting the dynamic reorganization of the microtubule network that is essential for cell division (mitosis). This disruption of microtubule function leads to cell cycle arrest and apoptosis (programmed cell death) in cancer cells. Methotrexate is a folate antimetabolite that inhibits DNA synthesis. Cisplatin is a platinum-based chemotherapy drug that damages DNA. Cyclophosphamide is an alkylating agent that also damages DNA.