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Migraine: Clinical manifestation.

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Recognizing the early signs and symptoms of a migraine, including prodromal and aura phases, can help in the timely management and prevention of attacks.
Updated On: Dec 10, 2025
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Solution and Explanation

Step 1: General Manifestations.
The clinical manifestations of migraine typically include:
(1) Headache - Unilateral, throbbing pain, often aggravated by physical activity, and commonly lasting from 4 to 72 hours.
(2) Nausea and Vomiting - Common symptoms that accompany the headache in many migraine sufferers.
(3) Photophobia and Phonophobia - Sensitivity to light and sound, often leading patients to seek a dark, quiet place during attacks.
(4) Aura (in some cases) - Visual disturbances like flashing lights, blind spots, or zigzag lines, and sensory disturbances like tingling or numbness, typically occurring before the headache.
Step 2: Additional Features.
(5) Aura Symptoms - These can involve vision changes, sensory disturbances, or speech difficulties and usually last between 5 to 60 minutes.
(6) Prodrome - Symptoms that can occur a day or two before the headache, including mood changes, food cravings, or neck stiffness.
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