Question

_____ is an example of aromatic nucleophilic substitution reaction.

• A. Gatterman Koch reaction
• B. Chichibabin
• C. Kolbes reaction
• D. Friedel-Crafts reaction

Answer 1

The Correct Option is B

The given question is to identify an example of an aromatic nucleophilic substitution reaction from the provided options. Let's analyze each option to determine the correct answer:

1. Gatterman Koch reaction: This is primarily an electrophilic aromatic substitution reaction used to introduce a formyl group (-CHO) into an aromatic ring. It doesn't involve nucleophilic substitution.
2. Chichibabin reaction: This is a classic example of an aromatic nucleophilic substitution reaction where a hydrogen atom on the aromatic ring (specifically pyridine) is substituted by an amino group (NH₂), typically using sodium amide (NaNH₂) in liquid ammonia. Hence, this matches the criteria for an aromatic nucleophilic substitution reaction.
3. Kolbe's reaction: Also known as Kolbe-Schmitt reaction, this is a carboxylation chemical reaction that converts phenols into salicylic acids. It involves an electrophilic aromatic substitution, not nucleophilic.
4. Friedel-Crafts reaction: This includes alkylation and acylation reactions which are examples of electrophilic aromatic substitution, where an aromatic compound is treated with a haloalkane or acyl chloride using a Lewis acid catalyst.

Based on the above analysis:

• The correct answer is Chichibabin, as it is the only reaction among the options given that is an aromatic nucleophilic substitution reaction.