List of top Organic Chemistry Questions asked in Graduate Pharmacy Aptitude Test

As per Bronsted-Lowry concept, acid is defined as:

Which of the following is a meta directing group:

The starting raw material for synthesis of lignocaine is:

In which limit test, Thioglycolic acid is used:

Famotidine contains:

Which functional group in drug molecules is most likely to undergo phase I metabolic oxidation by cytochrome P450 enzymes:

How many optical isomers are possible for lactic acid:

Which of the following is first prodrug for sulfonamide:

Which of the following is an aryl acetic acid derivative:

The IUPAC name of tartaric acid is:

Which of the following is easily nitrated using a mixture of \(HNO_3\) and \(H_2SO_4\) :

According to Oppenauer Oxidation reaction, oxidation of secondary alcohol to ketone by reagent (X) in acetone takes place, what is "X" :

Oppenauer Oxidation reaction

The reaction between napthalene and chromium trioxide in the presence of glacial acetic yields:

Establishing a complete structure of is more complex problem than others.

Match List I with List II:

List I		List II
A.	Penicillin	I.	Single cell protein
B.	Penicillin	II.	Ion exchange chromato- graphy for recovery
C.	Streptomycin	III.	Primary metabolite
D.	Amino acids	IV.	Phenyl acetic acid as precursor

Choose the correct answer from the options given below:

___activates G-protein gated potassium channel resulting in membrane hyperpolarization.

One of the following match is correct choose it:

Isoquinoline on treatment with oleum at 90°C yields majorly:

Predict the theoretical max value for the following compound using Woodward-Fieser rules. Base value for the compound is 215 nm:

Predict the theoretical max value for the following compound

What is the popular common name for a bioactive compound with chemical name of (m-hydroxyphenyl)-trimethyl ammonium methyl sulphate dimethyl carbomate?

Amphetamine undergoes one of the following metabolic reaction to convert to 1-phenyl-2-propanol metabolite via ketone formation:

Which among the following Cephalosporins has an unusual 5-thio-1,2,3,4-tetrazole substituent attached to core heterocyclic nucleus through a methylene bridge?

The C-2 epimer of D-glucose is:

_____ is an example of aromatic nucleophilic substitution reaction.

Identify pair of C₄ epimers:

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