Letters: P, O, T, I, C, A (all distinct). Vowels \(= \{O,I,A\}\) (3), consonants \(=\{P,T,C\}\) (3). Positions are \(1,2,3,4,5,6\); odd positions are \(1,3,5\).
Step 1: Place the vowels in the odd slots.
All three odd slots must be filled by the three vowels. They can be permuted in \(3!\) ways.
Step 2: Place the consonants in the even slots.
Even positions \(2,4,6\) are filled by P, T, C in \(3!\) ways.
Step 3: Multiply independent choices.
Total arrangements
\[
3!\times 3!=6\times 6=36.
\]
Sanity check (alternate view).
Total permutations of 6 distinct letters is \(6!=720\). Probability a random permutation has vowels in the three odd slots equals
\[
\frac{\binom30\,\binom33}{\binom63} \cdot \frac{3!\,3!}{6!}=\frac{1\cdot1}{20}\cdot \frac{36}{720}=\frac{36}{720},
\]
which again gives \(36\) favorable arrangements.
\[
\boxed{36}
\]