Question:

In both DNA and RNA, heterocyclic base and phosphate ester linkages are at 

Updated On: Sep 3, 2024
  • (A) C5 and C1 respectively of the sugar molecule
  • (B) C1 and C5 respectively of the sugar molecule
  • (C) C2 and C5 respectively of the sugar molecule
  • (D) C5 and C2 respectively of the sugar molecule
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The Correct Option is B

Approach Solution - 1

Explanation:
In DNA and RNA heterocyclic base and phosphate ester are at C1 and C5 respectively of the sugar molecule.
Hence, the correct option is (B).
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Approach Solution -2

Phosphate ester linkage is the covalent bond that will connect the sugar molecules with the backbone. This linkage occurs between 3’ carbon of one sugar to the 5’ carbon of the adjacent carbon. The phosphate will provide a negative charge and maintain the stability. 

On the other hand, the heterocyclic base is attached to the Carbon-1’ of both DNA and RNA sugar molecules. The bases present in them are adenine, guanine, cytosine, uracil and thymine. 

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