The two types of specialised cells which carry out the primary and secondary immune response:
1. B-cells (B lymphocytes): These cells are responsible for the production of antibodies during both the primary and secondary immune responses. The primary response occurs when the body encounters the pathogen for the first time, and the secondary response occurs during subsequent encounters with the same pathogen.
2. T-cells (T lymphocytes): These cells assist in the immune response by either helping B-cells produce antibodies (Helper T-cells) or directly killing infected cells (Cytotoxic T-cells).
A carpenter needs to make a wooden cuboidal box, closed from all sides, which has a square base and fixed volume. Since he is short of the paint required to paint the box on completion, he wants the surface area to be minimum.
On the basis of the above information, answer the following questions :
Find \( \frac{dS}{dx} \).
