Question:

If the sequence of one strand of DNA is written as follows: 

5'-ATGCATGCATGCATGCATGCATGCATGC-3' 

Write down the sequence of complementary strand in 5'→3' direction

Updated On: Oct 5, 2023
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Solution and Explanation

The DNA strands are complementary to each other with respect to base sequence. Hence, if the sequence of one strand of DNA is 

5'- ATGCATGCATGCATGCATGCATGCATGC − 3’

Then, the sequence of complementary strand in 5' to 3' direction will be 

3'- TACGTACGTACGTACGTACGTACGTACG − 5’ 

Therefore, the sequence of nucleotides on DNA polypeptide in 5' to 3' direction is 

5'- GCATGCATGCATGCATGCATGCATGCAT− 3’

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Concepts Used:

Transcription

The very first stage of gene expression is the procedure of transcription. In this procedure, mRNA is the place where the genetic information is stored which later aids in encoding a protein. In this process, the DNA strand acts as a guide in the making of mRNA. Despite the fact that there is one exception which is adenine base pairs with uracil instead of thymine.

Transcription Unit:

The transcription unit is a set of freshly combined RNA molecules that have been transcribed from DNA. The cause is to encode at least one gene. A protein that has been encoded or encrypted with a DNA transcription unit may have a coding sequence. Transcription has a lower copying fidelity rate when differentiated from DNA replication.

The Stages of Transcription:

The procedure of transcription is enzymatically catalyzed into three steps:

  1. Initiation
  2. Elongation
  3. Termination