Question

Identify the correct statement

• A. IUDs are generally inserted by the user herself.
• B. IUDs promote phagocytosis of sperms by WBC.
• C. Gametogenesis is suppressed by IUDs.
• D. IUDs are not suitable contraceptives for females.

Hint:

IUDs act locally in the uterus and one of their key functions is to enhance sperm destruction by white blood cells.

Answer 1

The Correct Option is B

Intrauterine devices (IUDs) are small contraceptive devices inserted into the uterus to prevent pregnancy. One of their mechanisms of action is to promote the phagocytosis (destruction) of sperms by white blood cells (WBCs), thus preventing fertilization. - Option (1) is incorrect: IUDs are typically inserted by a trained healthcare professional, not by the user herself.
- Option (3) is incorrect: IUDs do not suppress gametogenesis; they work primarily within the uterus to prevent fertilization or implantation.
- Option (4) is incorrect: IUDs are widely used and suitable contraceptives for females. Hence, the correct answer is option (2).

Answer 2

Intrauterine devices (IUDs) are a widely used method of reversible contraception. They are small, often T-shaped devices inserted into the uterus to prevent pregnancy. One important mechanism by which IUDs prevent fertilization is by inducing an inflammatory reaction in the uterine environment.

This inflammatory response attracts white blood cells (WBCs), such as macrophages and neutrophils, into the uterine cavity. These immune cells actively engulf and destroy sperm through a process called phagocytosis, thereby reducing the number of viable sperm that can reach and fertilize the egg.

Apart from promoting phagocytosis of sperms by WBCs, IUDs also alter the uterine lining to make it less receptive to implantation and may affect the motility of sperm and egg. However, their primary contraceptive effect is the prevention of fertilization through sperm destruction.

Therefore, the correct statement is that IUDs promote phagocytosis of sperms by white blood cells (WBCs), making fertilization unlikely and effectively preventing pregnancy.