Question:

Hypothyroidism is due to
A. High level of iodine in the diet
B. Enlargement of thyroid gland
C. Low levels of iodine in the diet
D. Increased levels of thyroxine

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Ensure adequate iodine intake in the diet to maintain normal thyroid function. Deficiency can lead to hypothyroidism and other health issues.
Updated On: May 21, 2025
  • A,B
  • B, C
  • C,D
  • A,C
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The Correct Option is B

Approach Solution - 1

Hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormones, primarily thyroxine. It can be caused by the following factors: - B. Enlargement of the thyroid gland (goiter) can be due to iodine deficiency, resulting in the body being unable to produce enough thyroid hormone. - C. Low levels of iodine in the diet is a primary cause of hypothyroidism, as iodine is necessary for thyroid hormone production. Thus, the correct answer is option (2) B, C.
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Approach Solution -2

Step 1: Understanding Hypothyroidism
Hypothyroidism is a medical condition in which the thyroid gland fails to produce enough thyroid hormones, particularly thyroxine (T4). This leads to a slow-down of the body’s metabolism and can cause fatigue, weight gain, and sensitivity to cold, among other symptoms.

Step 2: Role of Iodine in Thyroid Function
Iodine is a crucial mineral required for the synthesis of thyroid hormones. A deficiency of iodine in the diet prevents the thyroid gland from producing sufficient hormones, leading to hypothyroidism. This is particularly common in regions where iodine-rich foods are scarce.

Step 3: Thyroid Gland Enlargement (Goitre)
When iodine levels are low, the thyroid gland tries to compensate by enlarging, a condition known as goitre. This enlargement is a physical sign that the gland is underactive and is trying to trap more iodine from the bloodstream. Hence, enlargement of the thyroid gland is both a symptom and a consequence of hypothyroidism.

Step 4: Incorrect Options
Option A is incorrect because a high level of iodine typically does not cause hypothyroidism; in fact, excessive iodine can sometimes lead to hyperthyroidism or thyroiditis. Option D is also incorrect because increased levels of thyroxine are associated with hyperthyroidism, not hypo-thyroidism.

Step 5: Conclusion
The correct options are B and C. Hypothyroidism is caused by low iodine levels in the diet and often results in enlargement of the thyroid gland (goitre) as a compensatory mechanism.
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