Hypersensitivity reactions to penicillin are classified as Type B adverse drug reactions. Type B reactions are idiosyncratic, unpredictable, and not related to the drug's pharmacological action. They often involve immunological mechanisms, as is the case with penicillin allergies, which can manifest as various symptoms ranging from skin rashes to anaphylaxis. Type A reactions are predictable and related to the drug's known pharmacology (e.g., side effects). Types C and D reactions are usually delayed and related to chronic drug exposure (carcinogenic or teratogenic effects).