Step 1: Recall formula for optical isomers.
Maximum number of optical isomers is given by:
\[
2^n
\]
where \(n\) is the number of asymmetric carbon atoms. Step 2: Substitute given value.
\[
n = 4
\Rightarrow 2^4 = 16
\]
Step 3: Conclusion.
Therefore, 16 optical isomers are possible.