Step 1: Understand how hormone receptors work.
Hormones can either bind to receptors located on the surface of the target cell or inside the cell. Water-soluble hormones like peptides and catecholamines (e.g., epinephrine) cannot pass through the lipid membrane, so their receptors are located on the cell surface.
Step 2: Analyze the options.
Estrogen, Thyroxine, and Testosterone are lipid-soluble hormones that typically pass through the cell membrane and bind to intracellular receptors.
Epinephrine, on the other hand, is a water-soluble hormone (a catecholamine) and acts through receptors on the surface of target cells.
Conclusion: The hormone with receptors on the cell surface is Epinephrine (Option 3).