Question:

Friedel-Crafts reaction is observed in:

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Electron-withdrawing or coordinating groups hinder Friedel-Crafts reactions by disrupting electrophilic activation.
Updated On: Jun 8, 2025
  • \( \text{Nitrobenzene} \)
  • \( \text{Aniline} \)
  • \( \text{Both A and B} \)
  • \( \text{None of the above} \)
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The Correct Option is D

Solution and Explanation

Nitrobenzene and aniline deactivate benzene for Friedel-Crafts reactions, since nitro and amino groups withdraw electron density or coordinate strongly with Lewis acids, preventing successful alkylation/acylation.
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