Question

Enumerate the causes of recurrent pregnancy loss.

Hint:

Recurrent pregnancy loss often requires a thorough evaluation to identify the underlying cause, which may be multifactorial.

Answer 1

Step 1: Understanding the causes of recurrent pregnancy loss.
Recurrent pregnancy loss (RPL) refers to the occurrence of two or more consecutive miscarriages. The causes can include a variety of factors: genetic, anatomical, endocrine, and immune-related factors.

Step 2: Detailed explanation of each cause.
Genetic factors: Abnormal chromosomal conditions, such as balanced translocations, are a common cause.
Anatomical factors: Structural abnormalities in the uterus, such as fibroids or a septate uterus, can lead to RPL.
Endocrine factors: Disorders like thyroid dysfunction, diabetes, or polycystic ovary syndrome (PCOS) can increase the risk.
Immune factors: Autoimmune diseases or antiphospholipid syndrome can also lead to recurrent miscarriages.

Step 3: Conclusion.
All of the above factors can contribute to recurrent pregnancy loss, and they need to be carefully evaluated in the case of RPL.