Question:
During translation initiation in prokaryotes, a $GTP$ molecule is needed in
During translation initiation in prokaryotes, a $GTP$ molecule is needed in
Updated On: Jul 27, 2022
- association of 30S, mRNA with formyl-met-tRNA
- association of 50S subunit of ribosome with initiation complex
- formation of formyl-met-tRNA
- binding of 30 subunit of ribosome with mRNA
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The Correct Option is A
Solution and Explanation
During the process of translation an initial complex is formed between mRNA, $30 S$ ribosomal subunit and methionyl $t$ RNA. This complex is formed due to association of $IF _{1}, IF _{2}, IF _{3}$ initiation factors and GTP molecule.
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Concepts Used:
Translation
The translation is the process of converting nucleic acid information into amino acids. It also relates to the process of producing proteins from mRNA templates.
Components of Translation:
The main components of translation include :
- mRNA of both Eukaryotes and Prokaryotes
- tRNA - It helps in sending commands or transferring the information between protein and nucleic acids.
- Ribosomes - It contains ribosomal RNA and proteins, therefore, it is called the manufacturing unit of a cell.
- Enzymes - It is required for the formation of a peptide bond between the amino acids and also to attach amino acids to the accurate tRNA molecules.
- Proteins - They are the soluble factors, which are required for proper initiation, elongation and termination of translation.
Translation Process:
The three stages of translation are-
- Initiation involves assembling ribosomes around mRNA and activating amino acid and delivering it to the transfer RNA.
- Elongation is the process in which the RNA strand gets longer by adding amino acids.
- The termination process only involves releasing a polypeptide chain.