During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called?
CAAT box
GGTT box
AAAT box
TATA box
The Correct Option is D
Solution and Explanation
A TATA box is a specific DNA sequence that serves as a marker for where a genetic sequence can be interpreted and decoded. This sequence acts as a promoter, initiating the transcription process. The name "TATA box" originates from its well-preserved DNA sequence, which is typically TATAAA. In numerous eukaryotic genes, this conserved TATA box is situated 25-35 base pairs before the gene's transcription start site. The TATA box has the capacity to establish the direction of transcription and identifies the DNA strand that should be read. Recognition of the TATA box is carried out by the TATA-binding protein, or TBP, which directly attaches to the TATA box. TBP achieves this connection by folding its DNA binding domain into a semi-symmetrical saddle shape, with the DNA positioned between the two sides of the saddle.
so, the correct option is (D): TATA Box
Top Questions on Molecular Basis of Inheritance
Student to attempt either option-(A) or (B):
(A) Write the features a molecule should have to act as a genetic material. In the light of the above features, evaluate and justify the suitability of the molecule that is preferred as an ideal genetic material.
OR
(B) Differentiate between the following:- [(i)] Polygenic Inheritance and Pleiotropy
- [(ii)] Dominance, Codominance and Incomplete dominance
- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
Study the given molecular structure of double-stranded polynucleotide chain of DNA and answer the questions that follow.
(a) How many phosphodiester bonds are present in the given double-stranded polynucleotide chain?
(b) How many base pairs are there in each helical turn of double helix structure of DNA? Also write the distance between a base pair in a helix.
(c) In addition to H-bonds, what confers additional stability to the helical structure of DNA?- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
Study the given below single strand of deoxyribonucleic acid depicted in the form of a “stick” diagram with 5′ – 3′ end directionality, sugars as vertical lines and bases as single letter abbreviations and answer the questions that follow.
Name the covalent bonds depicted as (a) and (b) in the form of slanting lines in the diagram.
How many purines are present in the given “stick” diagram?
Draw the chemical structure of the given polynucleotide chain of DNA.- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
Use the given information to select the amino acid attached to the 3′ end of tRNA during the process of translation, if the coding strand of the structural gene being transcribed has the nucleotide sequence TAC.
- CBSE CLASS XII - 2025
- Biology
- Molecular Basis of Inheritance
- Distance between two consecutive base pairs of DNA is \rule{2cm}{0.1mm}
- CBSE Compartment XII - 2025
- Biology
- Molecular Basis of Inheritance
Questions Asked in NEET exam
- Two identical point masses P and Q, suspended from two separate massless springs of spring constants \(k_1\) and \(k_2\), respectively, oscillate vertically. If their maximum velocities are the same, the ratio of the amplitude of P to the amplitude of Q is :
- NEET (UG) - 2025
- Waves and Oscillations
A sphere of radius R is cut from a larger solid sphere of radius 2R as shown in the figure. The ratio of the moment of inertia of the smaller sphere to that of the rest part of the sphere about the Y-axis is :
- NEET (UG) - 2025
- Moment Of Inertia
- A microscope has an objective of focal length \(f_o = 2\) cm and an eyepiece of focal length \(f_e = 4\) cm. The tube length of the microscope is \(L = 40\) cm. If the distance of distinct vision of eye is \(D = 25\) cm, the magnification in the microscope is:
- NEET (UG) - 2025
- Optical Instruments
AB is a part of an electrical circuit (see figure). The potential difference \(V_A - V_B\), at the instant when current \(i = 2\) A and is increasing at a rate of 1 amp/second is:
- NEET (UG) - 2025
- Electromagnetic Induction and Inductance
- Twins are born to a family that lives next door to you. The twins are a boy and a girl. Which of the following must be true?
- NEET (UG) - 2025
- Genetics
Concepts Used:
Transcription
The very first stage of gene expression is the procedure of transcription. In this procedure, mRNA is the place where the genetic information is stored which later aids in encoding a protein. In this process, the DNA strand acts as a guide in the making of mRNA. Despite the fact that there is one exception which is adenine base pairs with uracil instead of thymine.
Transcription Unit:
The transcription unit is a set of freshly combined RNA molecules that have been transcribed from DNA. The cause is to encode at least one gene. A protein that has been encoded or encrypted with a DNA transcription unit may have a coding sequence. Transcription has a lower copying fidelity rate when differentiated from DNA replication.
The Stages of Transcription:
The procedure of transcription is enzymatically catalyzed into three steps:
- Initiation
- Elongation
- Termination