During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called?
CAAT box
GGTT box
AAAT box
TATA box
The Correct Option is D
Solution and Explanation
A TATA box is a specific DNA sequence that serves as a marker for where a genetic sequence can be interpreted and decoded. This sequence acts as a promoter, initiating the transcription process. The name "TATA box" originates from its well-preserved DNA sequence, which is typically TATAAA. In numerous eukaryotic genes, this conserved TATA box is situated 25-35 base pairs before the gene's transcription start site. The TATA box has the capacity to establish the direction of transcription and identifies the DNA strand that should be read. Recognition of the TATA box is carried out by the TATA-binding protein, or TBP, which directly attaches to the TATA box. TBP achieves this connection by folding its DNA binding domain into a semi-symmetrical saddle shape, with the DNA positioned between the two sides of the saddle.
so, the correct option is (D): TATA Box
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Concepts Used:
Transcription
The very first stage of gene expression is the procedure of transcription. In this procedure, mRNA is the place where the genetic information is stored which later aids in encoding a protein. In this process, the DNA strand acts as a guide in the making of mRNA. Despite the fact that there is one exception which is adenine base pairs with uracil instead of thymine.
Transcription Unit:
The transcription unit is a set of freshly combined RNA molecules that have been transcribed from DNA. The cause is to encode at least one gene. A protein that has been encoded or encrypted with a DNA transcription unit may have a coding sequence. Transcription has a lower copying fidelity rate when differentiated from DNA replication.
The Stages of Transcription:
The procedure of transcription is enzymatically catalyzed into three steps:
- Initiation
- Elongation
- Termination