Question:
Development of drug resistance is not generally associated with overexpression of which of the following transporters?
Development of drug resistance is not generally associated with overexpression of which of the following transporters?
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Folate receptors are not part of the typical efflux transporter family linked to drug resistance.
Updated On: Jun 16, 2025
- BCRP
- ABCB1
- MDR1
- Folate receptors
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The Correct Option is D
Solution and Explanation
While transporters like BCRP, ABCB1, and MDR1 are commonly overexpressed in drug-resistant cancer cells and are involved in efflux of drugs, folate receptors are mainly involved in nutrient uptake and are not typically associated with drug resistance mechanisms.
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