Question:

Describe the life cycle of HIV from the time of its entry into the human body till full-blown AIDS sets in.

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The progression from HIV infection to AIDS can take years and depends on the viral load and immune system strength.
Updated On: Jan 21, 2025
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Solution and Explanation

The HIV life cycle can be summarized as follows: 
Entry and Integration: The virus enters the host body and attaches to CD4 receptors on helper T-cells. It injects its RNA and viral enzymes into the host cell. 

Reverse Transcription: Viral RNA is converted into DNA by reverse transcriptase. 

Integration: The viral DNA integrates into the host genome with the help of integrase enzyme. 

Replication and Assembly: The host cell machinery is used to produce viral RNA and proteins. New viruses are assembled. 

Release and Maturation: Newly formed viruses bud off from the host cell, ready to infect other cells. Over time, the number of helper T-cells decreases, leading to immune system failure (AIDS).

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