Question:

Choose the correct statement regarding the GIFT (Gamete Intrafallopian Tube Transfer) procedure.

Updated On: Jun 11, 2024
  • Zygote is collected from a female donor and transferred to the uterus of recipient.
  • Ova are collected from a female donor and are transferred to the uterus of recipient
  • Ova collected from a female donor are transferred to the fallopian tube to facilitate zygote formation in the recipient
  • Zygote is collected from female donor and transferred to the fallopian tube of recipient.
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The Correct Option is C

Solution and Explanation

In GIFT, the gamete (ova) is collected from the female donor and is transferred into the fallopian tube. At the ampullary-isthmus junction of the fallopian tube, the fertilization process occurs.
If the embryo with more than eight blastomeres is transferred to the uterus of the mother or the surrogate mother, then this is called intrauterine transfer.
If the zygote (with up to $8$ blastomeres) is transferred to the fallopian tube, then it is called the zygote intrafallopian transfer (ZIFT).
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Concepts Used:

Infertility

Infertility is described as not being able to get pregnant in spite of having frequent, unprotected sex for not less than a year for most couples. Infertility may result from an issue with either you or your partner or a combination of factors that stops a pregnancy.

Symptoms:

The major symptom of infertility is not getting pregnant. There may be no other apparent symptoms. Sometimes, women with infertility may have irregular or missing menstrual periods. In some cases, men with infertility may have some signs of hormonal issues, like changes in hair growth or sexual function.

Causes of male infertility:

  • Abnormal sperm production or function
  • Problems with the delivery of sperm
  • Overexposure to certain environmental factors
  • Damage related to cancer and its treatment

Causes of female infertility

  • Ovulation disorders
  • Uterine or cervical abnormalities
  • Fallopian tube damage or blockage
  • Endometriosis
  • Primary ovarian insufficiency
  • Pelvic adhesions
  • Cancer and its treatment.