Choose the antigenic component of the viral infection Hepatitis B from the following options.
Show Hint
- Alum-adsorbed inactivated Hepatitis B surface antigen
- Alum-adsorbed recombinant Hepatitis B surface antigen
- Inactivated trivalent WHO-recommended strains
- Attenuated trivalent WHO-recommended strains
The Correct Option is B
Solution and Explanation
The Hepatitis B vaccine is not a live vaccine but a subunit vaccine. It contains purified surface antigen (HBsAg) produced using recombinant DNA technology in yeast cells.
Step 2: Role of adjuvant.
To increase the immune response, the recombinant HBsAg is adsorbed on alum (aluminum hydroxide), which acts as an adjuvant. This enhances antigen presentation and antibody production.
Step 3: Elimination of incorrect options.
- (A) Inactivated surface antigen is not correct because the vaccine is recombinant, not inactivated.
- (C) and (D) refer to influenza vaccines (trivalent strains), not Hepatitis B.
Step 4: Correct identification.
Thus, the correct component is alum-adsorbed recombinant Hepatitis B surface antigen.
Final Answer:
\[ \boxed{\text{Alum-adsorbed recombinant Hepatitis B surface antigen}} \]
Top Questions on Microbiology
Match the LIST-I with LIST-II.
\[ \begin{array}{|l|l|} \hline \textbf{LIST I (Pathogen)} & \textbf{LIST II (Detection methods)} \\ \hline A. \ \text{Legionella} & I. \ \text{Enzyme-linked immunosorbent assay (ELISA) or EIA for detection of P-24} \\ B. \ \text{HIV} & II. \ \text{Cartridge based nucleic acid amplification test (CBNAAT) Gene Xpert} \\ C. \ \text{Mycobacterium} & III. \ \text{Urinary antigen test} \\ D. \ \text{Salmonella typhi} & IV. \ \text{Widal test for antibody against both O and H antigens} \\ \hline \end{array} \]Match the LIST-I (Microbial pathogen) with LIST-II (Clinical syndromes):
\[ \begin{array}{|l|l|} \hline \textbf{LIST I (Microbial pathogen)} & \textbf{LIST II (Clinical syndromes)} \\ \hline A. \ \textbf{Haemophilus aegyptius} & I. \ Upper respiratory tract infection \\ B. \ \textbf{Haemophilus influenzae} & II. \ Pneumonia \\ C. \ \textbf{Haemophilus ducreyi} & III. \ Conjunctivitis \\ D. \ \textbf{Haemophilus haemolyticus} & IV. \ Chancroid (STD) \\ \hline \end{array} \]
Choose the correct answer from the options given below:
- HPV is responsible mainly for:
- What is the approximate incubation period in procedure of Widal Test for testing typhoid?
- Read the following statements.
A. Prions are inactivated by steam autoclaving at $\geq 121^{\circ}$C after treatment with 1M NaOH.
B. Prions contain genetic materials DNA or RNA.
C. Prions are extremely resistant to conventional disinfection and sterilization methods.
D. Prion infection do not elicit any detectable specific humoral or cellular immune response.
Questions Asked in CUET PG exam
Match List-I with List-II:
\[ \begin{array}{|l|l|} \hline \textbf{List-I (Name of Drug)} & \textbf{List-II (Indication)} \\ \hline A. \ \text{Baclofen} & I. \ \text{Spasticity} \\ B. \ \text{Diclofenac} & II. \ \text{Inflammatory pain} \\ C. \ \text{Gabapentin} & III. \ \text{Central or peripheral neurogenic pain} \\ D. \ \text{Amitryptiline} & IV. \ \text{Depression} \\ \hline \end{array} \]- CUET (PG) - 2025
- Pharmacology
Match List-I with List-II:
\[ \begin{array}{|l|l|} \hline \textbf{List-I (Ascending tract of the spinal cord)} & \textbf{List-II (Function)} \\ \hline A. \ \text{Lateral spinothalamic tract} & I. \ \text{Pain and temperature from opposite half of the body} \\ B. \ \text{Anterior spinothalamic tract} & II. \ \text{Vibratory sense} \\ C. \ \text{Fasciculus Cuneatus} & III. \ \text{Crude touch and pressure from opposite half of the body} \\ D. \ \text{Posterior spinocerebellar tract} & IV. \ \text{Unconscious proprioception to cerebellum} \\ \hline \end{array} \]- CUET (PG) - 2025
- Neurophysiology
Match List-I with List-II:
\[ \begin{array}{|l|l|} \hline \textbf{List-I (Muscle)} & \textbf{List-II (Nerve supply)} \\ \hline A. \ \text{Gluteus maximus} & I. \ \text{Ventral rami of S1, S2} \\ B. \ \text{Piriformis} & II. \ \text{Nerve to quadratus femoris} \\ C. \ \text{Gemellus inferior} & III. \ \text{Superior Gluteal nerve} \\ D. \ \text{Gluteus minimus} & IV. \ \text{Inferior gluteal nerve} \\ \hline \end{array} \]Match List-I with List-II:
\[ \begin{array}{|l|l|} \hline \textbf{List-I (Vaccines)} & \textbf{List-II (Their respective contents)} \\ \hline A. \ \text{Typhoid vaccine} & I. \ \text{Killed rickettsia} \\ B. \ \text{Typhus vaccine} & II. \ \text{Killed bacteria} \\ C. \ \text{Measles vaccine} & III. \ \text{Attenuated viruses} \\ D. \ \text{Smallpox vaccine} & IV. \ \text{Killed viruses} \\ \hline \end{array} \]- CUET (PG) - 2025
- Immunology
Match List-I with List-II
\[ \begin{array}{|l|l|} \hline \textbf{List-I} & \textbf{List-II} \\ \hline A. \ \text{Anterior/Ventral} & I. \ \text{Away from the midline of the body (outer side)} \\ B. \ \text{Inferior/Caudal} & II. \ \text{Towards the front of the body} \\ C. \ \text{Lateral} & III. \ \text{Towards the back of the body} \\ D. \ \text{Posterior/Dorsal} & IV. \ \text{Towards the lower part of the body} \\ \hline \end{array} \]- CUET (PG) - 2025
- Physiotherapy