Question

Assertion (A): Some experts believe that there must be more than 30,000 genes in human genome.
Reason (R): Unreliability of in silico gene prediction is responsible for reporting lesser number of genes in human genome.

• A. Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of the Assertion (A).
• B. Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation of the Assertion (A).
• C. Assertion (A) is true, but Reason (R) is false.
• D. Assertion (A) is false, but Reason (R) is true.

Hint:

In Assertion and Reason type questions, try to establish a clear link between the two statements before reaching a conclusion.

Answer 1

The Correct Option is A

Assertion (A): Some experts have posited the possibility of the human genome containing more than 30,000 genes based on preliminary estimates and expected complexity of the system. As the human genome project progressed, they realised the actual number of genes was less than initially anticipated. Reason (R): The reason is correct because it is true that *in silico* gene prediction is not fully reliable, especially with respect to non-coding regions and smaller genes. This has often resulted in a discrepancy between theoretical predictions and actual findings. Explanation: Since both are true, and Reason (R) provides a valid justification for the assertion, (A) is the correct option.