Question

Assertion (A): Aliphatic primary amines can be prepared by Gabriel phthalimide synthesis. Reason (R): Alkyl halides undergo nucleophilic substitution with anion formed by phthalimide.

• A. Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of the Assertion (A).
• B. Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation of the Assertion (A).
• C. Assertion (A) is true, but Reason (R) is false
• D. Assertion (A) is false, but Reason (R) is true.

Hint:

Gabriel synthesis is not suitable for aryl amines, as aryl halides do not undergo SN2 substitution.

Answer 1

The Correct Option is A

- Gabriel phthalimide synthesis is a method used to prepare primary aliphatic amines by reacting phthalimide with alkyl halides, forming an intermediate that hydrolyzes to yield the amine. - This occurs via nucleophilic substitution (SN2 mechanism), where the phthalimide anion attacks the alkyl halide. - Since both the assertion and reason are correct, and Reason (R) explains Assertion (A), option (A) is correct.