Question

Apart from TNF-alpha inhibitors, which IL-6 receptor antagonist has been found effective in treating arthritis?

• A. \( \text{Anakinra} \)
• B. \( \text{Leflunomide} \)
• C. \( \text{Rituximab} \)
• D. \( \text{Tocilizumab} \)

Hint:

IL-6 inhibitors help manage inflammatory conditions resistant to TNF-alpha blockers.

Answer 1

The Correct Option is D

Tocilizumab is an IL-6 receptor antagonist used in rheumatoid arthritis treatment. It blocks IL-6 signaling, reducing inflammation and autoimmune damage. TNF-alpha inhibitors are common for RA management, but IL-6 inhibition provides an alternative therapeutic pathway.