Question:

All or none law is not applicable for

Updated On: Aug 8, 2023
  • whole skeletal muscle
  • single skeletal muscle fibre
  • whole cardiac muscle
  • single smooth muscle fibre
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All or none law or Bowditchs law is a principle which states that response of a muscle nerve to a stimulus is not proportionate to the intensity of stimulus but is either present in full strength or completely absent. This law is applicable to single muscle fibre but entire muscle does not follow this law.
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Ans: All and none law is the functioning of the muscle fibres and how they respond to stimuli. According to this law, a muscle fibre will contract fully in response to a stimulus or it will not contract at all. This means that if the muscle a=has received a stimulus and reached its threshold then it will contract fully even though another stimulus occurs. But in the case of the whole skeletal muscle, the all and none law is not applicable at macroscopic level. The reason is that there are multiple muscles that are involved in the contraction and all the muscles have different threshold potential.Thus, the overall force of contraction of a whole muscle can vary. 

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