Question:

All of the following statements are true regarding neutrophil extracellular trapping (NET) except that

Updated On: Jun 18, 2025
  • It is detected in blood during sepsis
  • It is produced in response to bacterial infection
  • Mitochondrial DNA is seen
  • It is chromatin with antibacterial enzymes
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The Correct Option is C

Solution and Explanation

To solve the problem, we must evaluate each statement regarding neutrophil extracellular trapping (NET) and identify the incorrect one.
  • NETs are indeed detected in blood during sepsis. This statement is true as NETs play a role in the body's immune response to severe infections like sepsis.
  • NETs are produced in response to bacterial infection, which is a true statement. NETs trap and neutralize pathogens to prevent their spread.
  • The statement concerning mitochondrial DNA being seen in NETs is incorrect. NETs are composed primarily of nuclear DNA rather than mitochondrial DNA.
  • NETs are a combination of chromatin with antibacterial enzymes, which is a true statement. They contain histones and enzymes that provide antimicrobial properties.
Thus, the statement "Mitochondrial DNA is seen" is the false one regarding neutrophil extracellular trapping.
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