Question

All are increased in IDA except? 

• A. TIBC
• B. Soluble transferrin receptor
• C. Transferrin saturation
• D. Erythropoietin

Answer 1

The Correct Option is C

In the context of Iron Deficiency Anemia (IDA), several laboratory parameters are typically evaluated to understand the body's iron status. The parameters include:

• Total Iron Binding Capacity (TIBC): This is usually elevated in IDA as the body increases the production of transferrin to capture more iron.
• Soluble Transferrin Receptor: This marker is often increased in IDA, reflecting greater erythropoietic activity and iron demand.
• Erythropoietin: The production of this hormone, which stimulates red blood cell production, is increased in conditions of anemia such as IDA.
• Transferrin Saturation: This parameter is typically decreased in IDA because there is a reduced amount of iron available to saturate the transferrin being produced. Thus, the percentage of transferrin that is saturated with iron is decreased.

Hence, among the options given, Transferrin saturation is the parameter that is not increased in IDA; instead, it is decreased.