The relation between the amount of a radioactive element at time \( t \) and its half-life is given by the formula:
\[
N(t) = N_0 \left( \frac{1}{2} \right)^{t/T_{1/2}}
\]
where \( N_0 \) is the initial number of atoms, \( T_{1/2} \) is the half-life, and \( N(t) \) is the number of atoms at time \( t \). The ratio \( \frac{A}{B} = 1:16 \) implies that 4 half-lives have passed.
Thus, \( t = 12 \) hours.