Question

A fixative ........... the macromolecular components of a cell.

• A. Degrades
• B. Immobilizes
• C. Penetrates
• D. Granulates

Answer 1

The Correct Option is B

A fixative is a chemical substance used in microscopy and histology to preserve cells and tissues by stabilizing their macromolecular structures. 

Step 1: Understanding the Role of a Fixative - Fixatives work by cross-linking proteins, lipids, and nucleic acids, preventing degradation and movement. - This process immobilizes cellular components, allowing detailed structural study under a microscope. 

Step 2: Evaluating the Options 
- Option (A) - Incorrect: A fixative does not degrade macromolecules but preserves them. 
- Option (B) - Correct: Fixatives immobilize macromolecules, maintaining cell structure. 
- Option (C) - Incorrect: Some fixatives penetrate tissues, but their main function is preservation. 
- Option (D) - Incorrect: Fixatives do not cause granulation; they prevent breakdown. 

Step 3: Conclusion Since fixatives work by immobilizing macromolecules, the correct answer is option (B).