To determine the diagnosis of the 25-year-old male with a 2 cm thyroid nodule post-thyroidectomy, we need to assess the possible options based on the histology picture, a key diagnostic tool for thyroid conditions. Let's examine these options:
Papillary carcinoma thyroid: The most common type of thyroid cancer. Histologically, it exhibits characteristic features such as "Orphan Annie eye" nuclei, nuclear grooves, and psammoma bodies. The presence of these features would support this diagnosis.
Follicular adenoma: A benign encapsulated tumor composed of follicular cells. It lacks the nuclear features of papillary carcinoma, such as the specific nuclear changes.
Graves disease: An autoimmune disease leading to hyperthyroidism. Generally, the histology would show diffusely enlarged thyroid gland with hyperplastic follicles, not a discrete nodule.
Adenomatous goitre: Non-cancerous enlargement of the thyroid with multiple nodules, often displaying nodularity without the specific nuclear features of papillary carcinoma.
Among the given options, based on the characteristic histological features typically seen in papillary carcinoma (e.g., nuclear features), it aligns most closely with the description of the papillary carcinoma thyroid. Therefore, considering the typical microscopic appearance and common presentation, the correct diagnosis is:
