Question:
Write the product obtained when D-glucose reacts with \( H_2N - OH \).
Write the product obtained when D-glucose reacts with \( H_2N - OH \).
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Hydroxylamine reacts with aldehydes and ketones to form oximes, which are useful intermediates in organic synthesis.
Updated On: Feb 28, 2025
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Solution and Explanation
When D-glucose reacts with hydroxylamine (\( H_2N - OH \)), it forms an oxime. The aldehyde group of D-glucose reacts with hydroxylamine to form a stable oxime, with the general formula \( R - C = N - OH \), where R is the remainder of the glucose molecule. In this reaction, the glucose aldehyde undergoes nucleophilic addition to form the corresponding oxime.
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