Question

Write the etiopathology of midtrimester abortions.

Hint:

In midtrimester abortions, the investigation of maternal conditions and infections is crucial for identifying underlying causes.

Answer 1

Step 1: Understanding midtrimester abortions.
Midtrimester abortions refer to pregnancy losses occurring between 12 to 24 weeks of gestation. The causes can vary, and often, a combination of factors contribute.

Step 2: Detailed explanation of each factor.
Infections: Infections such as TORCH (Toxoplasmosis, Rubella, Cytomegalovirus, Herpes simplex) can lead to abortion.
Chromosomal abnormalities: Genetic disorders like Down syndrome, Turner syndrome, and other chromosomal abnormalities are frequent causes.
Uterine abnormalities: Malformations of the uterus like bicornuate uterus or cervical insufficiency can result in pregnancy loss.
Endocrine disorders: Conditions like uncontrolled diabetes or thyroid disease can also contribute to midtrimester abortions.

Step 3: Conclusion.
The etiopathology of midtrimester abortion involves infections, chromosomal abnormalities, uterine structural issues, and endocrine imbalances.