Question

Write the chemical reaction involved in Gabriel phthalimide synthesis.

Hint:

- Gabriel Phthalimide Synthesis is specific for primary amines. - Secondary and tertiary amines are not formed in this reaction.

Answer 1

Gabriel phthalimide synthesis is used for the preparation of primary amines.
Step 1: Formation of N-Alkyl Phthalimide \[ \text{Phthalimide} + KOH \rightarrow \text{Potassium Phthalimide} \] \[ \text{Potassium Phthalimide} + R-X \rightarrow \text{N-Alkyl Phthalimide} \] Step 2: Hydrolysis to Form Primary Amine \[ \text{N-Alkyl Phthalimide} + NaOH \rightarrow \text{Primary Amine} + \text{Phthalic Acid} \]