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Williamson's synthesis

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Williamson's synthesis involves an SN2 reaction mechanism and is widely used for asymmetric ether synthesis.

Updated On: Mar 6, 2025
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Solution and Explanation

Step 1: Williamson's synthesis is used for the preparation of ethers. 

Step 2: Reaction: \[ R-O^- + R'-X \rightarrow R-O-R' + X^- \] where \( R'X \) is an alkyl halide and \( R-O^- \) is an alkoxide ion. 

Step 3: Example: \[ C_2H_5ONa + CH_3I \rightarrow C_2H_5OCH_3 + NaI \]

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