Step 1: Understand the law of thermodynamics that predicts reaction completion.
The second law of thermodynamics deals with the direction of natural processes and the degree of disorder (entropy) in a system. It predicts the spontaneity and completion of chemical reactions.
Step 2: Conclusion.
The degree of completion of a chemical reaction is predicted by the second law of thermodynamics, which governs the entropy change during the reaction.
Final Answer:
\[
\boxed{\text{Second law}}
\]