Question

Which oral hypoglycemic agent increases the levels of incretin hormone by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4):

• A. Metformin
• B. Pioglitazone
• C. Sitagliptin
• D. Glipizide

Hint:

Sitagliptin is a DPP-4 inhibitor that boosts incretin levels, enhancing insulin secretion and improving glucose control in patients with type 2 diabetes.

Answer 1

The Correct Option is C

Sitagliptin is an oral hypoglycemic agent that works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). DPP-4 normally deactivates incretin hormones, which help to increase insulin secretion and decrease glucagon secretion in response to meals. By inhibiting DPP-4, Sitagliptin increases the levels of incretin hormones, improving blood sugar control.