Step 1: Understand what Vitamin B12 is.
Vitamin B12, also known as cobalamin, is a complex organometallic compound that plays an essential role in red blood cell formation, neurological function, and DNA synthesis.
Step 2: Identify the central metal ion in Vitamin B12.
The name “cobalamin” comes from cobalt (Co), which is the central metal ion in the corrin ring of the Vitamin B12 molecule. The cobalt atom is coordinated at the center of this ring, which is similar in structure to a porphyrin ring but slightly contracted.
Step 3: Eliminate the other options.
Mn (Manganese): Not present in Vitamin B12.
Zn (Zinc): Important in enzymes like carbonic anhydrase, but not in B12.
Cu (Copper): Found in proteins like ceruloplasmin but not in B12.
Step 4: Confirm the correct answer.
Only Cobalt (Co) is associated with Vitamin B12, making option (2) the correct one.